Collection 

Biofilm-related infections

Submission status
Closed
Submission deadline

Biofilms are bacterial clusters embedded within an extracellular matrix that adhere both to each other and to cells throughout the body. An estimated 80% of chronic microbial infections across a range of tissues are thought to involve biofilms, with examples including chronic otitis media, recurrent urinary tract infection and endocarditis. Biofilm-related infections are particularly challenging to treat, given that their structure allows for evasion of the immune response and supports resistance to antibiotics. Development of new approaches to biofilm-related infection prevention, treatment and management is therefore critical.

This Collection gathers research that increases our understanding of the progression of biofilm-related infections and explores associated strategies for their diagnosis, prevention and treatment.

Biofilm of antibiotic resistant bacteria, closeup view. Image can be used for any rod-shaped bacteria, Escherichia coli, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Klebsiella and other

Editors

  • Mario Alberto Flores-Valdez

    Centro de Investigación y Asistencia en Tecnología y diseño del Estado de Jalisco, A.C. (CIATEJ), Mexico

  • Raffaele Zarrilli

    University of Napoli “Federico II”, Italy

Mario Alberto Flores-Valdez is a Professor at the Medical and Pharmaceutical Biotechnology Unit of CIATEJ, A.C. (Guadalajara, Jalisco, Mexico; 2007-present). His research focuses on Tuberculosis, particularly in developing recombinant BCG strains as vaccine candidates as well as studying the role of biofilms in this disease. Prof Flores-Valdez has been an Editorial Board Member for Scientific Reports since 2022.

 

 

Raffaele Zarrilli is a Professor of Hygiene and Public Health at the University of Napoli Federico II, Italy. His research interests include the genomic epidemiology of multi-drug resistant Acinetobacter baumannii and Klebsiella pneumoniae and the mechanisms of acquisition of antimicrobial resistance in Gram-negative bacteria. Prof Zarrilli has been an Editorial Board Member for Scientific Reports since 2017.