Welcome to the Nature Biotechnology and Nature Reviews Drug Discovery joint Web Focus on Antivirals. This Web Focus, supported by Pfizer (principal sponsor) and Gilead (supporting sponsor), hosts a collection of Reviews, Research Highlights and Commentaries covering the science and business of antiviral drug R&D. It also includes an online-only NPG library of recent research papers and review content from other NPG journals. The articles on this page and selected content from the NPG library are freely available from December 2007 until June 2008.



Editorials

Beyond interferon

doi:10.1038/nbt1207-1375

Nature Biotechnology 25, 1375

Three decades of antiviral drugs

Erik De Clercq

doi:10.1038/nrd2485

Nature Reviews Drug Discovery 6, 941

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News & Analysis

Hepatitis C: staying the course

Ken Garber

doi:10.1038/nbt1207-1379

Nature Biotechnology 25, 1379-1381

Profile: Ian Frazer

Mark Ratner

doi:10.1038/nbt1207-1377

Nature Biotechnology 25, 1377

An Audience With: Tadataka Yamada

doi:10.1038/nrd2481

Nature Reviews Drug Discovery 6, 950

HIV combination products

Lisette Oversteegen, Mansi Shah & Holger Rovini

doi:10.1038/nrd2448

Nature Reviews Drug Discovery 6, 951-952

Antivirals become a broader enterprise

Jeffrey L Fox

doi:10.1038/nbt1207-1395

Nature Biotechnology 25, 1395-1402

Patentability issues surrounding antivirals

Deborah L Lu, Angela M Collison & Thomas J Kowalski

doi:10.1038/nbt1207-1403

Nature Biotechnology 25, 1403-1404

Recent patent applications in antivirals

doi:10.1038/nbt1207-1405

Nature Biotechnology 25, 1405

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Opinion and Comment

Antivirals—an increasingly healthy investment

Brian McCarthy

doi:10.1038/nbt1207-1390

Nature Biotechnology 25, 1390-1393

Systems biology and the host response to viral infection

Seng-Lai Tan, Gopinath Ganji, Bryan Paeper, Sean Proll & Michael G Katze

doi:10.1038/nbt1207-1383

Nature Biotechnology 25, 1383-1389

Bioinformatics prediction of HIV coreceptor usage

Thomas Lengauer, Oliver Sander, Saleta Sierra, Alexander Thielen & Rolf Kaiser

doi:10.1038/nbt1371

Nature Biotechnology 25, 1407-1408

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Research Highlights

Antivirals: Mirror image inhibition

Monica Hoyos Flight

doi:10.1038/nrd2474

Nature Reviews Drug Discovery 6, 955

Antivirals: MicroRNA versus virus: uncovering new layers of complexity

Alexandra Flemming

doi:10.1038/nrd2472

Nature Reviews Drug Discovery 6, 957

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Perspectives

HIV drug development: the next 25 years

Charles Flexner

doi:10.1038/nrd2336

Nature Reviews Drug Discovery 6, 959-966

The war against influenza: discovery and development of sialidase inhibitors

Mark von Itzstein

doi:10.1038/nrd2400

Nature Reviews Drug Discovery 6, 967-974

Albinterferon alpha-2b: a genetic fusion protein for the treatment of chronic hepatitis C

G Mani Subramanian, Michele Fiscella, Araba Lamousé-Smith, Stefan Zeuzem & John G McHutchison

doi:10.1038/nbt1364

Nature Biotechnology 25, 1411-1419

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Reviews

Interferons at age 50: past, current and future impact on biomedicine

Ernest C. Borden, Ganes C. Sen, Gilles Uze, Robert H. Silverman, Richard M. Ransohoff, Graham R. Foster & George R. Stark

doi:10.1038/nrd2422

Nature Reviews Drug Discovery 6, 975-990

The way forward in HCV treatment — finding the right path

Michael P. Manns, Graham R. Foster, Jürgen K. Rockstroh, Stefan Zeuzem, Fabien Zoulim & Michael Houghton

doi:10.1038/nrd2411

Nature Reviews Drug Discovery 6, 991-1000

The design of drugs for HIV and HCV

Erik De Clercq

doi:10.1038/nrd2424

Nature Reviews Drug Discovery 6, 1001-1018

The growth and potential of human antiviral monoclonal antibody therapeutics

Wayne A Marasco & Jianhua Sui

doi:10.1038/nbt1363

Nature Biotechnology 25, 1421-1434

RNA interference against viruses: strike and counterstrike

Joost Haasnoot, Ellen M Westerhout & Ben Berkhout

doi:10.1038/nbt1369

Nature Biotechnology 25, 1435-1443

Genetic therapies against HIV

John J Rossi, Carl H June & Donald B Kohn

doi:10.1038/nbt1367

Nature Biotechnology 25, 1444-1454

Careers & Recruitment

Antiviral drug discovery and development

doi:10.1038/nrd2483

Nature Reviews Drug Discovery 6, 1019

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Extra navigation

Supported by

Principal Sponsor


Pfizer

Supporting Sponsor


Gilead

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