Welcome to the Nature Biotechnology and Nature Reviews Drug Discovery joint Web Focus on Antivirals. This Web Focus, supported by Pfizer (principal sponsor) and Gilead (supporting sponsor), hosts a collection of Reviews, Research Highlights and Commentaries covering the science and business of antiviral drug R&D. It also includes an online-only NPG library of recent research papers and review content from other NPG journals. The articles on this page and selected content from the NPG library are freely available from December 2007 until June 2008.
Editorials
Beyond interferon
doi:10.1038/nbt1207-1375
Nature Biotechnology 25, 1375
Three decades of antiviral drugs
Erik De Clercq
doi:10.1038/nrd2485
Nature Reviews Drug Discovery 6, 941
News & Analysis
Hepatitis C: staying the course
Ken Garber
doi:10.1038/nbt1207-1379
Nature Biotechnology 25, 1379-1381
Profile: Ian Frazer
Mark Ratner
doi:10.1038/nbt1207-1377
Nature Biotechnology 25, 1377
An Audience With: Tadataka Yamada
doi:10.1038/nrd2481
Nature Reviews Drug Discovery 6, 950
HIV combination products
Lisette Oversteegen, Mansi Shah & Holger Rovini
doi:10.1038/nrd2448
Nature Reviews Drug Discovery 6, 951-952
Antivirals become a broader enterprise
Jeffrey L Fox
doi:10.1038/nbt1207-1395
Nature Biotechnology 25, 1395-1402
Patentability issues surrounding antivirals
Deborah L Lu, Angela M Collison & Thomas J Kowalski
doi:10.1038/nbt1207-1403
Nature Biotechnology 25, 1403-1404
Recent patent applications in antivirals
doi:10.1038/nbt1207-1405
Nature Biotechnology 25, 1405
Opinion and Comment
Antivirals—an increasingly healthy investment
Brian McCarthy
doi:10.1038/nbt1207-1390
Nature Biotechnology 25, 1390-1393
Systems biology and the host response to viral infection
Seng-Lai Tan, Gopinath Ganji, Bryan Paeper, Sean Proll & Michael G Katze
doi:10.1038/nbt1207-1383
Nature Biotechnology 25, 1383-1389
Bioinformatics prediction of HIV coreceptor usage
Thomas Lengauer, Oliver Sander, Saleta Sierra, Alexander Thielen & Rolf Kaiser
doi:10.1038/nbt1371
Nature Biotechnology 25, 1407-1408
Research Highlights
Antivirals: Mirror image inhibition
Monica Hoyos Flight
doi:10.1038/nrd2474
Nature Reviews Drug Discovery 6, 955
Antivirals: MicroRNA versus virus: uncovering new layers of complexity
Alexandra Flemming
doi:10.1038/nrd2472
Nature Reviews Drug Discovery 6, 957
Perspectives
HIV drug development: the next 25 years
Charles Flexner
doi:10.1038/nrd2336
Nature Reviews Drug Discovery 6, 959-966
The war against influenza: discovery and development of sialidase inhibitors
Mark von Itzstein
doi:10.1038/nrd2400
Nature Reviews Drug Discovery 6, 967-974
Albinterferon -2b: a genetic fusion protein for the treatment of chronic hepatitis C
G Mani Subramanian, Michele Fiscella, Araba Lamousé-Smith, Stefan Zeuzem & John G McHutchison
doi:10.1038/nbt1364
Nature Biotechnology 25, 1411-1419
Reviews
Interferons at age 50: past, current and future impact on biomedicine
Ernest C. Borden, Ganes C. Sen, Gilles Uze, Robert H. Silverman, Richard M. Ransohoff, Graham R. Foster & George R. Stark
doi:10.1038/nrd2422
Nature Reviews Drug Discovery 6, 975-990
The way forward in HCV treatment — finding the right path
Michael P. Manns, Graham R. Foster, Jürgen K. Rockstroh, Stefan Zeuzem, Fabien Zoulim & Michael Houghton
doi:10.1038/nrd2411
Nature Reviews Drug Discovery 6, 991-1000
The design of drugs for HIV and HCV
Erik De Clercq
doi:10.1038/nrd2424
Nature Reviews Drug Discovery 6, 1001-1018
The growth and potential of human antiviral monoclonal antibody therapeutics
Wayne A Marasco & Jianhua Sui
doi:10.1038/nbt1363
Nature Biotechnology 25, 1421-1434
RNA interference against viruses: strike and counterstrike
Joost Haasnoot, Ellen M Westerhout & Ben Berkhout
doi:10.1038/nbt1369
Nature Biotechnology 25, 1435-1443
Genetic therapies against HIV
John J Rossi, Carl H June & Donald B Kohn
doi:10.1038/nbt1367
Nature Biotechnology 25, 1444-1454
Careers & Recruitment
Antiviral drug discovery and development
doi:10.1038/nrd2483
Nature Reviews Drug Discovery 6, 1019