Collection 

Receptor tyrosine kinases in disease

Submission status
Closed
Submission deadline

Receptor tyrosine kinases (RTKs) are vital cellular signaling molecules. However, because of their ability to rapidly amplify extracellular signals, RTKs and their associated signaling pathways are often implicated in disease. Although many RTKs are targetable with tyrosine kinase inhibitors, patients almost inevitably develop resistance. Understanding the roles of these signaling pathways in disease can help us understand how to best target them and identify mechanisms of resistance.

This collection is dedicated to the role of RTKs in disease, including understanding how these signaling pathways promote pathogenesis, identifying novel mutations, improving treatment methods, and examining downstream signaling pathways.

Left: inactive monomer, right: active dimer after EGF binding.

Editors

  • Ira Daar

    National Cancer Institute, USA

  • Paul Dent

    Virginia Commonwealth University, USA

  • Michael Simons

    MD Yale University School of Medicine, USA

Submitting a paper for consideration

 

To submit your manuscript for consideration at Scientific Reports as part of this Collection, please follow the steps detailed on this page. On the first page of our online submission system, under “I’m submitting:” select the option “any other article type”. Once logged in you can submit your manuscript to a Collection by selecting “Guest Edited Collection”, under the “Choose the appropriate manuscript type” message, and clicking “Continue”. Then when filling out the manuscript information, select the "Receptor tyrosine kinases in disease" Collection from the alphabetical list on the “Springer Nature Subject Category” tab. Authors should express their interest in the Collection in their cover letter.

Accepted papers are published on a rolling basis as soon as they are ready.

In addition to papers on Receptor tyrosine kinases in disease, Scientific Reports welcomes all original research in the field of Cell biology. To browse our latest articles in Cell biology click here.

 

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