Collection 

Antifungals and Resistance

Submission status
Open
Submission deadline

The Fungal Kingdom includes a phenomenal diversity of organisms, some of which pose devastating threats to agriculture, human health, and biodiversity. There is a limited number of antifungal agents, and the emergence of resistance threatens the efficacy of existing antifungals. There is an urgent need for new strategies to thwart emerging and resistant fungal pathogens alongside the need for greater understanding of one-health aspects. This collection aims to publish cutting-edge research on methods to mitigate fungal infections  and to combat the emergence of resistance. 

Diverse topics will be covered, including:

  • Current antifungals used in medicine, agriculture, and animal husbandry
  • Mechanisms enabling the evolution of resistance to antifungal agents
  • Emergence of resistance to antifungals in the environment and the clinic
  • Reservoirs of antifungal resistance
  • Effects of antifungals on microbiomes
  • Microbiomes as sources of new antifungals
  • Approaches for discovery of new antifungals
  • Identifying targets of new antifungals
  • Antifungal combinations and synergy
  • Antifungal stewardship
  • Policy aspects of antifungal development and usage

This Collection supports and amplifies research related to SDG 3.

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Microscopic image of growing molds or mold fungus and spores

Editors

  • Matthew Fisher

    Professor of Fungal Disease Epidemiology, Faculty of Medicine, School of Public Health, Imperial College London, UK

  • Leah Cowen

    University of Toronto Toronto, ON, Canada

Articles