Immune system and cardiovascular disease

Immune system activation or dysregulation has a major role in the development and progression of many cardiovascular diseases. To highlight the importance of the innate and adaptive immune responses in the pathophysiology of cardiovascular diseases, Nature Reviews Cardiology brings together a collection of Reviews and news articles with the latest advances in this field. The articles in this collection discuss topics including the role of inflammation in the pathophysiology of atrial fibrillation, the involvement of macrophages and mast cells in cardiometabolic disease, the cardioprotective effects of regulatory T cells, and the current evidence on the use of anti-inflammatory therapies for atherosclerosis. Improving our understanding of the inflammatory processes involved in the pathophysiology of cardiovascular diseases can lead to new opportunities for the management of these patients.


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