Abstract
Acute spinal cord injury patients were assigned alternately to a control and a heparin prophylaxis group to determine the effect of 5,000 μ sodium heparin subcutane-ously every 12 hours on the incidence of venous thrombosis as detected by impedance plethysmography of the lower extremities. Venous thrombosis was unexpectedly uncommon in both the control (1 of 17) and the heparinised (1 of 15) group, suggesting an unidentified, overriding prophylactic factor.
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Brach, B B, Moser, K M, Cedar, L, Minteer, M & Convery, R (1977). Venous thrombosis in acute spinal cord paralysis. J. Trauma, 17, 289.
Flanc, C, Kakkar, V V & Clark, M B (1969). Postoperative deep-vein thrombosis, effect of intensive prophylaxis. Lancet, 1, 477.
International Multicenter Trial. (1975). Prevention of fatal postoperative pulmonary embolism by low doses of heparin. Lancet, 2, 45.
Johnston, K W, Kakkar, V V, Spindler, J J, Corrigan, T P & Fossard, D P (1974). A simple method for detecting deep venous thrombosis. Am. J. Surg., 127, 349.
Rabinov, K & Paulin, S (1972). Roentgen diagnosis of venous thrombosis in the leg. Arch. Surg., 104, 134.
Rossier, A B & Brunner, U (1964). Zur initialen behandlung der frischen traumatischen querschnitts läsion. Schweiz. Med. Wschr., 94, 362.
Sager, S (1974). Low dose heparin prophylaxis against fatal postoperative pulmonary embolism. Brit. Med. J., 2, 153.
Silver, J R & Moulton, A (1970). Prophylactic anticoagulant therapy against pulmonary embolism in acute paraplegia. Brit. Med. J., 2, 338.
Todd, J W, Frisbie, J H, Rossier, A B, Adams, D F, Als, A V, Armenia, R J, Sasahara, A A & Tow, D E (1976). Deep venous thrombosis in acute spinal cord injury: a comparison of 125I fibrinogen leg scanning, impedance plethysmography and venography. Paraplegia, 14, 50.
Van Hove, E (1978). Prevention of thrombophlebitis in spinal injury patients. Paraplegia, 16, 332.
Walsh, J J & Tribe, C (1965). Phlebo-thrombosis and pulmonary embolism in paraplegia. Paraplegia, 3, 209.
Watson, N (1968). Venous thrombosis and pulmonary embolism in spinal cord injury. Paraplegia, 6, 113.
Watson, N (1978). Anticoagulant therapy in the prevention of venous thrombosis and pulmonary embolism in the spinal cord injury. Paraplegia, 16, 265.
Wheeler, H B, O'Donnell, J A, Anderson, F A, Jr. & Benedict, K, Jr. (1974). Occlusive impedance phlebography: a diagnostic procedure for venous thrombosis and pulmonary embolism. Prog. Cardiovasc. Dis., 17, 199.
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Frisbie, J., Sasahara, A. Low dose heparin prophylaxis for deep venous thrombosis in acute spinal cord injury patients: a controlled study. Spinal Cord 19, 343–346 (1981). https://doi.org/10.1038/sc.1981.65
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DOI: https://doi.org/10.1038/sc.1981.65
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