Sinusoidal vessels are specialized vascular structures required for hematopoiesis. A new study demonstrates a role for VEGF-C–VEGFR3 signaling in the development of sinusoidal vessels and a previously unappreciated reciprocal regulatory relationship between VE-cadherin and VEGFR3.
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McCord, T.J., Kontos, C.D. VEGF-C and VE-cadherin: balancing sinusoidal and lymphatic angiogenesis. Nat Cardiovasc Res 1, 976–977 (2022). https://doi.org/10.1038/s44161-022-00164-z
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DOI: https://doi.org/10.1038/s44161-022-00164-z
