Intensive blood pressure control has been suggested to reduce the risk of adverse cardiovascular events. However, the effect of intensive blood pressure control on cardiac conduction system disease has not been clarified. Our study in older patients with hypertension identified no effect of intensive blood pressure control on cardiac conduction system diseases.
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References
Kusumoto, F. M. et al. 2018 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation 140, e382–e482 (2019). This paper reports the evaluation and management of patients with cardiac conduction system diseases.
Bussink, B. E. et al. Right bundle branch block: prevalence, risk factors, and outcome in the general population: results from the Copenhagen City Heart Study. Eur. Heart J. 34, 138–146 (2013). This paper presents the association of hypertension with right bundle branch block.
Frimodt-Møller, E. K. et al. Association between intensive vs standard blood pressure control and incident left ventricular conduction disease: a post hoc analysis of the SPRINT randomized clinical trial. JAMA Cardiol 8, 612–616 (2023). A study that reports that intensive blood pressure control lowers the risk of left ventricular conduction disease.
Zhang, W. et al. Trial of intensive blood-pressure control in older patients with hypertension. N. Engl. J. Med. 385, 1268–1279 (2021). This paper reports that intensive blood pressure control reduces adverse cardiovascular event risk in older Chinese patients.
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This is a summary of: Zhao, S. et al. Incidence and prognosis of cardiac conduction system diseases in hypertension: the STEP trial. Nat. Aging https://doi.org/10.1038/s43587-024-00591-6 (2024).
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Intensive blood pressure control does not lower risk of cardiac conduction system diseases. Nat Aging 4, 449–450 (2024). https://doi.org/10.1038/s43587-024-00605-3
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DOI: https://doi.org/10.1038/s43587-024-00605-3