Using a multi-omics strategy, we uncovered location- and sex-specific aging heterogeneity of the large intestine in monkeys and identified a range of potential gut aging regulators. We explored the roles of several regulators in intestinal function and lifespan in Caenorhabditis elegans. Finally, we investigated potential links between gut aging and colorectal cancer.
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This is a summary of: Wang, X. et al. Age-, sex- and proximal–distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates. Nat. Aging, https://doi.org/10.1038/s43587-024-00572-9 (2024).
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Decoding regulators of gut aging in nonhuman primates. Nat Aging 4, 289–290 (2024). https://doi.org/10.1038/s43587-024-00577-4
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DOI: https://doi.org/10.1038/s43587-024-00577-4
