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Centile curves for following intrinsic capacity across adulthood

Nature Aging volume 3, pages 1482–1483 (2023)Cite this article

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Intrinsic capacity (IC) — a metric that reflects the composite of a person’s physical and mental capacities — varies across adulthood and between individuals of the same age. People with an IC below the tenth percentile suffer from a high burden of diseases, frailty, disabilities and recent falls.

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Fig. 1: Distribution of IC score in adults aged 20–102 years old.

References

  1. Kingston, A. et al. Is late-life dependency increasing or not? A comparison of the Cognitive Function and Ageing Studies (CFAS). Lancet 390, 1676–1684 (2017). An article that investigates the number of years lived at different levels of dependency (low, medium or high) between 1991 and 2011 among people aged 65 years old or older.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Beard, J. R. et al. The world report on ageing and health: a policy framework for healthy ageing. Lancet 387, 2145–2154 (2016). An article that summarizes the world report on ageing and health released by the WHO.

    Article  PubMed  Google Scholar 

  3. Beard, J. R. & Chen, M. Intrinsic capacity as a composite outcome measure: opportunities and challenges. J. Nutr. Heal. Aging. 27, 398–400 (2023). One of the first papers to highlight that assessment of IC trajectories against population norms could allow monitoring of health status in the second half of life.

    Article  CAS  Google Scholar 

  4. de Souto Barreto, P. et al. The INSPIRE research initiative: a program for GeroScience and healthy aging research going from animal models to humans and the healthcare system. J. Frailty Aging 10, 86–93 (2021). A methodological paper that details the INSPIRE research program.

    PubMed  Google Scholar 

  5. Cole, T. J. The LMS method for constructing normalized growth standards. Eur. J. Clin. Nutr. 44, 45–60 (1990). An article that details the LMS method.

    CAS  PubMed  Google Scholar 

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This is a summary of: Lu, W.-H. et al. Reference centiles for intrinsic capacity throughout adulthood and their association with clinical outcomes: a cross-sectional analysis from the INSPIRE-T cohort. Nat. Aging https://doi.org/10.1038/s43587-023-00522-x (2023).

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Centile curves for following intrinsic capacity across adulthood. Nat Aging 3, 1482–1483 (2023). https://doi.org/10.1038/s43587-023-00534-7

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