Our understanding of the genetics that underlies healthy aging can be improved by integrating complementary traits related to chronological and biological aging. We present a multitrait genome-wide association study that reflects the genetics of a broad healthy aging factor and use genetics methods to investigate potential therapeutic relationships among various drug targets.
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References
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This is a summary of: Rosoff, D. B. et al. Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging. Nat. Aging https://doi.org/10.1038/s43587-023-00455-5 (2023).
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A shared genetics approach to understand the architecture underlying healthy aging. Nat Aging 3, 919–920 (2023). https://doi.org/10.1038/s43587-023-00461-7
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DOI: https://doi.org/10.1038/s43587-023-00461-7
