High-affinity tau-PET was used to apply the Braak neuropathological staging system for Alzheimer’s disease in vivo. Tau-PET can be used to stage Alzheimer’s disease from presymptomatic to clinical dementia phases in people, while also providing a framework to model the natural history of Alzheimer’s disease using biomarkers.
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This is a summary of: Therriault, J. et al. Biomarker modeling of Alzheimer’s disease using PET-based Braak staging. Nat. Aging https://doi.org/10.1038/s43587-022-00204-0 (2022).
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Tau-PET-based biological staging of Alzheimer’s disease in vivo. Nat Aging 2, 471–472 (2022). https://doi.org/10.1038/s43587-022-00232-w
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DOI: https://doi.org/10.1038/s43587-022-00232-w
