Inflammation is known to be elevated with progressive age. In this issue, Sayed et al. identify a group of circulating cytokines that correlate with health decline in aging, particularly the chemokine CXCL9. The findings offer a new understanding of how wellbeing and biological resilience are independent from chronological age.
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Acknowledgements
M.L.I.-A. is supported by the National Institutes of Health (R35HL140014).
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Iruela-Arispe, M.L. An inflammatory clock for healthy aging. Nat Aging 1, 574–575 (2021). https://doi.org/10.1038/s43587-021-00085-9
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DOI: https://doi.org/10.1038/s43587-021-00085-9