Tailoring immunotherapy with liquid biopsy

Immunotherapy has changed the treatment paradigm for patients with cancer, but patient selection, response assessment and treatment duration require further refinement. A recent study reports that the kinetics of circulating tumor DNA reflect response and resistance to immunotherapy treatment across multiple cancer types and could be used to tailor treatment.

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Fig. 1: The kinetics pf ctDNA track the response to pembrolizumab treatment in the INSPIRE clinical trial.


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Correspondence to Jeanne Tie.

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Tie, J. Tailoring immunotherapy with liquid biopsy. Nat Cancer 1, 857–859 (2020).

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