Two modelling studies offer compelling evidence that less-than-perfect adherence to HIV pre-exposure prophylaxis can still provide reasonable protection for cisgender women — providing optimism for a more person-centered approach and lower discontinuation rates.
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Acknowledgements
M.S. is a National Institute for Health and Care Research (NIHR) global research professor (NIHR 301634) and receives funding from the Bill and Melinda Gates Foundation (BMGF) (INV-033650); US National Institute of Health (NIH) (5R01MH114560-03); and the Wellcome Trust (082384/Z/07/Z). F.C. and M.S. receive funding from Wellcome Trust (214280/z/18/Z). F.C. also receives funding from BMGF (OPP1136774). N.C. is supported by a NIHR and Wellcome Trust International Training fellowship (224309/Z/21/Z).
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Shahmanesh, M., Chimbindi, N. & Cowan, F.M. Person-centered HIV PrEP for cisgender women. Nat Med 29, 2707–2708 (2023). https://doi.org/10.1038/s41591-023-02618-8
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DOI: https://doi.org/10.1038/s41591-023-02618-8