Injured human donor lungs deemed unsuitable for immediate transplantation may be successfully recovered by connection into the circulation of a porcine host with perfusion and ventilation ex vivo for 24 hours.
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Acknowledgements
A.J.F. and J.H.D. are supported by the National Institute for Health Research Blood and Transplant Research Unit in Organ Donation and Transplantation at the University of Cambridge and Newcastle University and in partnership with NHS Blood and Transplant. The views expressed are those of the authors and not necessarily those of the National Institute for Health Research, the Department of Health and Social Care or NHS Blood and Transplant .
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A.J.F. and J.H.D. have received, via their host institution, research grant funding from XVIVO Sweden, which manufactures organ-perfusion devices and perfusate solutions.
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Fisher, A.J., Dark, J.H. Ex vivo repair of human donor lungs for transplantation. Nat Med 26, 1015–1016 (2020). https://doi.org/10.1038/s41591-020-0967-4
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DOI: https://doi.org/10.1038/s41591-020-0967-4
