Colonization of the mucosal tissues by iNKT cells was thought to be linked to the first contact with the environment. New research demonstrates that this process is regulated by and dependent on embryonic macrophages.
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Bertrand, L., Toubal, A. & Lehuen, A. Macrophages make the bed for early iNKT cells. Nat Immunol 22, 681–682 (2021). https://doi.org/10.1038/s41590-021-00938-w
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DOI: https://doi.org/10.1038/s41590-021-00938-w