Host cell cholesterol is often exploited by pathogens for entry and egress. Two new studies elucidate a new interferon-inducible mechanism by which cells limit plasma membrane cholesterol to promote antibacterial defense.
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Dang, E.V., Madhani, H.D. & Vance, R.E. Cholesterol in quarantine. Nat Immunol 21, 716–717 (2020). https://doi.org/10.1038/s41590-020-0712-7
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DOI: https://doi.org/10.1038/s41590-020-0712-7
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