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Issues with combining incompatible and sterile insect techniques

Matters Arising to this article was published on 03 February 2021

The Original Article was published on 17 July 2019

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References

  1. Zheng, X. et al. Incompatible and sterile insect techniques combined eliminate mosquitoes. Nature 572, 56–61 (2019).

    Article  CAS  Google Scholar 

  2. Dobson, S. L., Fox, C. W. & Jiggins, F. M. The effect of Wolbachia-induced cytoplasmic incompatibility on host population size in natural and manipulated systems. Proc. R. Soc. Lond. B 269, 437–445 (2002).

    Article  Google Scholar 

  3. Calvitti, M., Moretti, R., Skidmore, A. R. & Dobson, S. L. Wolbachia strain wPip yields a pattern of cytoplasmic incompatibility enhancing a Wolbachia-based suppression strategy against the disease vector Aedes albopictus. Parasit. Vectors 5, 254 (2012).

    Article  Google Scholar 

  4. Rasgon, J. L. in Transgenesis and the Management of Vector-Borne Disease (ed. Aksoy, S.), 114–125 (Springer, 2008).

  5. Garcia, G. A., Hoffmann, A. A., Maciel-de-Freitas, R. & Villela, D. A. M. Aedes aegypti insecticide resistance underlies the success (and failure) of Wolbachia population replacement. Sci. Rep. 10, 63 (2020).

    Article  ADS  CAS  Google Scholar 

  6. Moretti, R., Marzo, G. A., Lampazzi, E. & Calvitti, M. Cytoplasmic incompatibility management to support Incompatible Insect Technique against Aedes albopictus. Parasit. Vectors 11 (Suppl. 2), 649 (2018).

    Article  Google Scholar 

  7. Puggioli, A., Calvitti, M., Moretti, R. & Bellini, R. wPip Wolbachia contribution to Aedes albopictus SIT performance: advantages under intensive rearing. Acta Trop. 164, 473–481 (2016).

    Article  Google Scholar 

  8. Mains, J. W., Brelsfoard, C. L., Rose, R. I. & Dobson, S. L. Female adult Aedes albopictus suppression by Wolbachia-infected male mosquitoes. Sci. Rep. 6, 33846 (2016).

    Article  ADS  CAS  Google Scholar 

  9. Moretti, R. et al. Combining Wolbachia-induced sterility and virus protection to fight Aedes albopictus-borne viruses. PLoS Negl. Trop. Dis. 12, e0006626 (2018).

    Article  Google Scholar 

  10. Caputo, B. et al. A bacterium against the tiger: preliminary evidence of fertility reduction after release of Aedes albopictus males with manipulated Wolbachia infection in an Italian urban area. Pest Manag. Sci. 76, 1324–1332 (2020).

    Article  CAS  Google Scholar 

  11. Zhang, D., Lees, R. S., Xi, Z., Gilles, J. R. L. & Bourtzis, K. Combining the sterile insect technique with Wolbachia-based approaches: II - A safer approach to Aedes albopictus population suppression programmes, designed to minimize the consequences of inadvertent female release. PLoS One 10, e0135194 (2015).

    Article  Google Scholar 

  12. Bond, J. G. et al. Optimization of irradiation dose to Aedes aegypti and Ae. albopictus in a sterile insect technique program. PLoS One 14, e0212520 (2019).

    Article  CAS  Google Scholar 

  13. Johnson, K. N. N. The impact of Wolbachia on virus infection in mosquitoes. Viruses 7, 5705–5717 (2015).

    Article  CAS  Google Scholar 

  14. Lu, P., Bian, G., Pan, X. & Xi, Z. Wolbachia induces density-dependent inhibition to dengue virus in mosquito cells. PLoS Negl. Trop. Dis. 6, e1754 (2012).

    Article  Google Scholar 

  15. Demirbas-Uzel, G. et al. Combining paratransgenesis with SIT: impact of ionizing radiation on the DNA copy number of Sodalis glossinidius in tsetse flies. BMC Microbiol. 18 (Suppl. 1), 160 (2018).

    Article  CAS  Google Scholar 

  16. Chouin-Carneiro, T. et al. Wolbachia strain wAlbA blocks Zika virus transmission in Aedes aegypti. Med. Vet. Entomol. 34, 116–119 (2020).

    Article  CAS  Google Scholar 

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Acknowledgements

We thank E. Lampazzi for her contribution to the research activity related to this topic and A. Serrao for contributing to acquisition of funding to support our research program.

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Correspondence to Riccardo Moretti.

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Moretti, R., Calvitti, M. Issues with combining incompatible and sterile insect techniques. Nature 590, E1–E2 (2021). https://doi.org/10.1038/s41586-020-03164-w

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