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CLINICAL TRIALS

Striking a balance in rheumatoid arthritis prevention trials

The discovery that autoantibodies and other factors can predict the future onset of rheumatoid arthritis (RA) has encouraged the development of clinical trials looking at RA prevention. Although an exciting area of research, finding an approach that results in the successful completion of an RA prevention trial is challenging.

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Fig. 1: Balancing factors related to study design and participation in RA prevention trials.

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Correspondence to Kevin D. Deane.

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O’Neil, L.J., Deane, K.D. Striking a balance in rheumatoid arthritis prevention trials. Nat Rev Rheumatol (2021). https://doi.org/10.1038/s41584-021-00627-w

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