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The human-infection potential of emerging tick-borne viruses is a global public health concern

Nature Reviews Microbiology volume 21, pages 215–217 (2023)Cite this article

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Although numerous tick-borne viruses are seemingly apathogenic in humans, a number of emerging tick-borne viruses have been recently identified to possess human-infection potential, with more yet to be discovered. Here, we call for greater research efforts to better delineate their precise disease burden and threats posed to global public health.

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Fig. 1: A phylogeny-like schematic diagram illustrating representative tick-borne nairoviruses.

References

  1. Balakrishnan, V. S. WHO launches global initiative for arboviral diseases. Lancet Microbe 3, e407 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

  2. Guglielmone, A. A. et al. The Argasidae, Ixodidae and Nuttalliellidae (Acari: Ixodida) of the world: a list of valid species names. Zootaxa 2528, 1–28 (2010).

    Article  Google Scholar 

  3. Centers for Disease Control and Prevention. Reported cases of notifiable diseases and rates per 100,000, excluding U.S. territories - United States; 2018. Centers for Disease Control and Prevention https://wonder.cdc.gov/nndss/static/2018/annual/2018-table1.html (2022).

  4. Vandegrift, K. J. & Kapoor, A. The ecology of new constituents of the tick virome and their relevance to public health. Viruses 11, 529–541 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Ma, J. et al. Identification of a new orthonairovirus associated with human febrile illness in China. Nat. Med. 27, 434–439 (2021).

    Article  CAS  PubMed  Google Scholar 

  6. Zhou, H. et al. Tamdy virus in Ixodid ticks infesting Bactrian camels, Xinjiang, China, 2018. Emerg. Infect. Dis. 25, 2136–2138 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. McMullan, L. K. et al. A new phlebovirus associated with severe febrile illness in Missouri. N. Engl. J. Med. 367, 834–841 (2012).

    Article  CAS  PubMed  Google Scholar 

  8. Kosoy, O. I. et al. Novel thogotovirus associated with febrile illness and death, United States, 2014. Emerg. Infect. Dis. 21, 760–764 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Wang, Z. D. et al. A new segmented virus associated with human febrile illness in China. N. Engl. J. Med. 380, 2116–2125 (2019).

    Article  CAS  PubMed  Google Scholar 

  10. Dong, Z. et al. Human Tacheng tick virus 2 infection, China, 2019. Emerg. Infect. Dis. 27, 594–598 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgements

This work was supported by the Academic Promotion Programme of Shandong First Medical University (2019QL006).

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Authors and Affiliations

  1. School of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji’nan, China

    Hong Zhou

  2. School of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji’nan, China

    Lin Xu & Weifeng Shi

  3. Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

    Weifeng Shi

  4. Shanghai Institute of Virology, Shanghai Jiao Tong University School of Medicine, Shanghai, China

    Weifeng Shi

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  1. Hong Zhou
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  2. Lin Xu
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Correspondence to Weifeng Shi.

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Zhou, H., Xu, L. & Shi, W. The human-infection potential of emerging tick-borne viruses is a global public health concern. Nat Rev Microbiol 21, 215–217 (2023). https://doi.org/10.1038/s41579-022-00845-3

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