Strong multidisciplinary support and political commitment have helped Spain become one of the countries most likely to eliminate hepatitis C. In this Comment, we set out six key elements of the Spanish elimination effort that can serve as a model elsewhere and the remaining barriers to overcome.
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References
Gamkrelidze, I. et al. Progress towards hepatitis C virus elimination in high-income countries: an updated analysis. Liver Int. 41, 456–463 (2021).
Ministry of Health, Social Services and Equality. Strategic Plan for Tackling Hepatitis C in the Spanish National Health System (Ministry of Health, Social Services and Equality, 2015).
Ministry of Health, Social Services and Equality. Guía de Cribado de la infección por el VHC [Spanish] (Ministry of Health, Social Services and Equality, 2020).
Crespo, J. et al. A call for the comprehensive diagnosis of viral hepatitis as a key step towards its elimination. Liver Int. 43, 1145–1147 (2023).
Calleja, J. L. et al. Ten steps to eliminating hepatitis C in hospitals. Nat. Rev. Gastroenterol. Hepatol. 19, 481–483 (2022).
Cuadrado, A. et al. Microenvironment eradication of hepatitis C: a novel treatment paradigm. Am. J. Gastroenterol. 113, 1639–1648 (2018).
Llaneras, J. et al. OS052 - clinical impact and cost-effectiveness of hepatitis C testing in an emergency department in Barcelona, Spain. J. Hepatol. 77, S44 (2022).
Politi, J. et al. Favorable impact in hepatitis C-related mortality following free access to direct-acting antivirals in Spain. Hepatology 75, 1247–1256 (2022).
World Health Organization. Global health sector strategies on, respectively, HIV, viral hepatitis and sexually transmitted infections for the period 2022-2030 (WHO, 2022).
World Health Organization. Criteria for validation of elimination of viral hepatitis B and C: report of 7 country pilots (WHO, 2022).
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J. Crespo has been a consultant and/or speaker and/or participated in sponsored clinical trials and/or received grants and research support from Gilead Sciences, AbbVie, MSD, Shionogi, Intercept Pharmaceuticals, Janssen Pharmaceuticals Inc., Celgene and Alexion, outside of the submitted work. He is also a member of the Scientific Committee of the Strategic Plan for the Management of Hepatitis C of the Spanish National Health System. J. Cabezas declares lecture fees from, grants from and advisory board participation for Gilead and AbbVie, outside of the submitted work. J.L.C. declares consultant and lectures fees from Gilead Sciences, AbbVie, MSD and Roche, outside of the submitted work. M.B. declares speaker fees from and advisory board participation for Gilead, AbbVie and Janssen and a grant from Gilead, outside of the submitted work. J.V.L. acknowledges grants and speaker fees from AbbVie, Gilead Sciences, MSD and Roche Diagnostics to his institution, speaker fees from Intercept, Janssen, Novo Nordisk and ViiV and consulting fees from Novavax, outside of the submitted work. He also acknowledges support to ISGlobal from the grant CEX2018-000806-S funded by MCIN/AEI/10.13039/501100011033 and the ‘Generalitat de Catalunya’ through the CERCA Program, outside of the submitted work.
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Crespo, J., Cabezas, J., Calleja, J.L. et al. The path to successful hepatitis C elimination in Spain. Nat Rev Gastroenterol Hepatol 20, 689–690 (2023). https://doi.org/10.1038/s41575-023-00813-z
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DOI: https://doi.org/10.1038/s41575-023-00813-z
