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Equitable partnerships and the path to inclusive, innovative and impactful human microbiome research

Practical recommendations on achieving equitability in biomedical research can advance essential efforts to balance research representation. In this Comment, we highlight how to generate interoperable and robust datasets, engage in thoughtful partnerships with researchers across geographies and cultures, and embrace innovative opportunities to push microbiome research beyond the gut and beyond bacteria.

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Fig. 1: Improving representation in microbiome research.


  1. Abdill, R. J., Adamowicz, E. M. & Blekhman, R. Public human microbiome data are dominated by highly developed countries. PLoS Biol. 20, e3001536 (2022).

    Article  CAS  Google Scholar 

  2. Atutornu, J., Milne, R., Costa, A., Patch, C. & Middleton, A. Towards equitable and trustworthy genomics research. eBioMedicine 76, 103879 (2022).

    Article  Google Scholar 

  3. Ramsay, M. et al. H3Africa AWI-Gen Collaborative Centre: a resource to study the interplay between genomic and environmental risk factors for cardiometabolic diseases in four sub-Saharan African countries. Glob. Health Epidemiol. Genomics 1, e20 (2016).

    Article  CAS  Google Scholar 

  4. Wonkam, A. et al. “Black Lives Matter and Black Research Matters”: the African Society of Human Genetics’ call to halt racism in science. Mol. Biol. Cell 33, vo2 (2022).

    Article  CAS  Google Scholar 

  5. Callaway, E. South Africa’s San people issue ethics code to scientists. Nature 543, 475–476 (2017).

    Article  CAS  Google Scholar 

  6. Han, H.-R. et al. Exploring community engaged research experiences and preferences: a multi-level qualitative investigation. Res. Involv. Engagem. 7, 19 (2021).

    Article  Google Scholar 

  7. Anuar, T. S., Salleh, F. M. & Moktar, N. Soil-transmitted helminth infections and associated risk factors in three Orang Asli tribes in Peninsular Malaysia. Sci. Rep. 4, 4101 (2014).

    Article  CAS  Google Scholar 

  8. Rubel, M. A. et al. Lifestyle and the presence of helminths is associated with gut microbiome composition in Cameroonians. Genome Biol. 21, 122 (2020).

    Article  CAS  Google Scholar 

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The authors thank D. Maghini and S. Hazelhurst for their thoughtful insights and partnership in an equitable research space, the Stanford Center for Innovation in Global Health and the nonprofit Global Oncology, Inc. for their partnership and guidance in learning how to carry out more equitable research. O.H.O. is supported by the AWI-Gen project grant from the National Human Genome Research Institute (U54HG006938) as part of the H3A Consortium.

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Correspondence to Ami S. Bhatt.

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Human Microbiome Initiative of select endogamous populations of India:

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Oduaran, O.H., Bhatt, A.S. Equitable partnerships and the path to inclusive, innovative and impactful human microbiome research. Nat Rev Gastroenterol Hepatol 19, 683–684 (2022).

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