Opportunities of twin research in gastroenterology

According to a meta-analysis of twin research studies, only a minority addressed gastrointestinal diseases, and mainly IBD and IBS. Here, we discuss similarities and differences between twin research in IBD and IBS, using these diseases as an example of the potential benefits that twin studies can offer gastroenterology.

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Correspondence to Paul Enck.

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Competing interests

M.G.-S. has served as an adviser and speaker for Heel, as a speaker for Schwabe and as an adviser for Yakult. P.E. received an unrestricted grant from SymbioPharm, served as adviser for Allergan, Almirall, AstraZeneca, Boehringer, Biocodex, Ferring, GA, Heel, SymbioPharm, TEVA, and UCB and as speaker for Almirall, Bayer/Steigerwald, Biogene, Boehringer, Chiesi, Heel and Sanofi. G.H. received unrestricted grants from Bayer, Commonwealth Laboratories, Falk Foundation and Takeda and served as speaker for Schwabe.

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MaTCH Meta-Analysis of Twin Correlations and Heritability: http://match.ctglab.nl/#/home

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Goebel-Stengel, M., Holtmann, G. & Enck, P. Opportunities of twin research in gastroenterology. Nat Rev Gastroenterol Hepatol 15, 325–326 (2018). https://doi.org/10.1038/s41575-018-0002-0

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