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Endocrine disrupting chemicals are a threat to hormone health: a commentary on behalf of the ESE

Nature Reviews Endocrinology volume 20, pages 187–188 (2024)Cite this article

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The European Society of Endocrinology (ESE), representing 20,000 endocrinologists, is concerned about the effect of endocrine disrupting chemicals (EDCs) on endocrine health, particularly thyroid and gonadal function. The policy strategies of the ESE aim to minimize overall exposure of humans to EDCs and to stimulate funding for research at the level of the European Union.

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References

  1. Richardson, K. et al. Earth beyond six of nine planetary boundaries. Sci. Adv. 9, eadh2458 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

  2. Gore, A. C. et al. EDC-2: The Endocrine Society’s second scientific statement on endocrine-disrupting chemicals. Endocr. Rev. 36, E1–E150 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. EUR-Lex. Communication from the commission to the European parliament, the council, the European Economic and Social Committee and the Committee of the Regions. Chemicals Strategy for Sustainability Towards a Toxic-Free Environment. https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=COM%3A2020%3A667%3AFIN (2020).

  4. Muir, D. C. G., Getzinger, G. J., McBride, M. & Ferguson, P. L. How many chemicals in commerce have been analyzed in environmental media? A 50 year bibliometric analysis. Environ. Sci. Technol. 57, 9119–9129 (2023).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  5. Wang, Z., Walker, G. W., Muir, D. C. G. & Nagatani-Yoshida, K. Toward a global understanding of chemical pollution: a first comprehensive analysis of national and regional chemical inventories. Environ. Sci. Technol. 54, 2575–2584 (2020).

    Article  ADS  CAS  PubMed  Google Scholar 

  6. Kassotis, C. D. et al. Endocrine-disrupting chemicals: economic, regulatory, and policy implications. Lancet Diabetes Endocrinol. 8, 719–730 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Köhrle, J. & Frädrich, C. Thyroid hormone system disrupting chemicals. Best Pract. Res. Clin. Endocrinol. Metab. 35, 101562 (2021).

    Article  PubMed  Google Scholar 

  8. Caporale, N. et al. From cohorts to molecules: Adverse impacts of endocrine disrupting mixtures. Science. 375, eabe8244 (2022).

    Article  CAS  PubMed  Google Scholar 

  9. Frederiksen, H. et al. High urinary phthalate concentration associated with delayed pubarche in girls. Int. J. Androl. 35, 216–226 (2012).

    Article  CAS  PubMed  Google Scholar 

  10. Vinnars, M. T., Bixo, M. & Damdimopoulou, P. Pregnancy-related maternal physiological adaptations and fetal chemical exposure. Mol. Cell. Endocrinol. 578, 112064 (2023).

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

The authors are grateful to Dirk De Rijdt (European Society of Endocrinology (ESE)) and Mischa van Eimeren (ESE) for providing key material from the EDC working group of the ESE for this commentary.

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Authors and Affiliations

  1. Medizinische Klinik und Poliklinik IV, LMU Klinikum, LMU München, München, Germany

    Martin Reincke

  2. MRC Laboratory of Medical Sciences, London, UK

    Wiebke Arlt

  3. Institute of Clinical Sciences, Imperial College London, London, UK

    Wiebke Arlt

  4. Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden

    Pauliina Damdimopoulou

  5. Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Huddinge, Stockholm, Sweden

    Pauliina Damdimopoulou

  6. Institut für Experimentelle Endokrinologie, Charité–Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

    Josef Köhrle

  7. Institut Cochin, Inserm U1016, CNRS UMR8104, Université Paris-Cité, Paris, France

    Jerome Bertherat

Authors
  1. Martin Reincke
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  2. Wiebke Arlt
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  3. Pauliina Damdimopoulou
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  4. Josef Köhrle
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  5. Jerome Bertherat
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Corresponding author

Correspondence to Martin Reincke.

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Competing interests

The authors declare no competing interests.

Additional information

Related links

Classification, Packing, and Labeling of Chemical Substances and Mixtures Regulation: https://environment.ec.europa.eu/topics/chemicals/classification-labelling-and-packaging-chemicals_en

European Hormone Day: https://www.ese-hormones.org/what-we-do/outreach/european-hormone-day/

Goal 3.9: https://sdgs.un.org/goals/goal3#targets_and_indicators

Known or suspected EDCs: https://edlists.org/the-ed-lists

Registration, Evaluation, Authorisation and Restriction of Chemicals regulation: https://environment.ec.europa.eu/topics/chemicals/reach-regulation_en

The Milano declaration: https://www.ese-hormones.org/what-we-do/outreach/european-hormone-day/the-milano-declaration/

White paper: https://www.ese-hormones.org/publications/directory/ese-white-paper/

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Reincke, M., Arlt, W., Damdimopoulou, P. et al. Endocrine disrupting chemicals are a threat to hormone health: a commentary on behalf of the ESE. Nat Rev Endocrinol 20, 187–188 (2024). https://doi.org/10.1038/s41574-024-00958-0

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