Bone marrow adipose tissue secretes adipokines and is involved in glucose and lipid metabolism. The confined bone marrow cavity could partially explain the resistance of bone marrow adipose tissue to insulin-mediated glucose uptake and its role in systemic energy regulation.
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Shen, W., Heymsfield, S.B. Bone marrow adipose tissue function — is space a constraint?. Nat Rev Endocrinol 16, 543–544 (2020). https://doi.org/10.1038/s41574-020-0400-6
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DOI: https://doi.org/10.1038/s41574-020-0400-6