Jessica D. Forbes and colleagues found that infants who received formula early in life were more likely to be overweight at 1 year of age than those exclusively breastfed. Formula feeding was associated with altered intestinal microbiome characteristics at 3 months. These findings link early-life formula feeding and an altered microbiome with subsequent overweight.
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The authors are supported by U01AI222285, from the National Institutes of Health and the C & D Fund to M.B. The authors thank I. Goldberg for his critical insights.
The authors declare no competing interests.
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Mueller, E., Blaser, M. Breast milk, formula, the microbiome and overweight. Nat Rev Endocrinol 14, 510–511 (2018). https://doi.org/10.1038/s41574-018-0066-5
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