Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Genetics

Genome editing prevents hypertrophic cardiomyopathy in mice

Nature Reviews Cardiology volume 20, page 211 (2023)Cite this article

Subjects

Colleagues from the Olson and Seidman laboratories have published two papers in Nature Medicine demonstrating the effectiveness of genome-editing approaches to correct a genetic variant in preclinical models of hypertrophic cardiomyopathy (HCM). The findings indicate the potential utility of base editing to treat a range of cardiac diseases caused by monogenic variants.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Get just this article for as long as you need it

$39.95

Learn more

Prices may be subject to local taxes which are calculated during checkout

References

Original articles

Related article

  • Nishiga, M. et al. The use of new CRISPR tools in cardiovascular research and medicine. Nat. Rev. Cardiol. 19, 505–521 (2022)

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Nature Reviews Cardiology http://www.nature.com/nrcardio/

    Gregory B. Lim

Authors
  1. Gregory B. Lim
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Gregory B. Lim.

Rights and permissions

Reprints and Permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lim, G.B. Genome editing prevents hypertrophic cardiomyopathy in mice. Nat Rev Cardiol 20, 211 (2023). https://doi.org/10.1038/s41569-023-00852-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41569-023-00852-8

Search

Advanced search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research