Cardiac hypertrophy
Cardiac hypertrophy is the abnormal enlargement, or thickening, of the heart muscle, resulting from increases in cardiomyocyte size and changes in other heart muscle components, such as extracellular matrix. Causes can be physiological for example, the amount of exercise performed by an athlete or pathological for example, as a result of hypertension or valvular disease.
Latest Research and Reviews
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Research
| Open Access
A compartment-based myocardial density approach helps to solve the native T1 vs. ECV paradox in cardiac amyloidosis
Scientific Reports 12, 21755 -
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Research
| Open Access
MYBPC3 deficiency in cardiac fibroblasts drives their activation and contributes to fibrosis
Cell Death & Disease 13, 948 -
Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential
A maladaptive feedback mechanism between the extracellular matrix and cytoskeleton contributes to hypertrophic cardiomyopathy pathophysiology
A compartment-based myocardial density approach helps to solve the native T1 vs. ECV paradox in cardiac amyloidosis
Alteration in tyrosine phosphorylation of cardiac proteome and EGFR pathway contribute to hypertrophic cardiomyopathy
MYBPC3 deficiency in cardiac fibroblasts drives their activation and contributes to fibrosis
Prevalence, incidence and mortality of hypertrophic cardiomyopathy based on a population cohort of 21.9 million in China
From heart to blood: LTBP-2 is a promising biomarker for pulmonary arterial hypertension
Myosin modulators move forward with FDA approval of mavacamten
Piezo1 senses pressure overload and initiates cardiac hypertrophy
Piezo1 links mechanosensation to cardiac growth
Metabolic dysregulation drives endoreplication in heart disease