In breast cancer metastasized to bone, the mineralization of collagen regulates integrin-mediated mechanosignalling, inducing a less proliferative phenotype in breast cancer cells.
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Ernst, C., Wang, H. Bone mineral slows down breast cancer cells. Nat. Biomed. Eng 7, 1346–1347 (2023). https://doi.org/10.1038/s41551-023-01122-1
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DOI: https://doi.org/10.1038/s41551-023-01122-1