Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

MECHANOPATHOLOGY

Compressive tumours cause neuronal damage

Nature Biomedical Engineering volume 3, pages 171–172 (2019)Cite this article

Subjects

By compressing blood vessels and neurons, globular tumours in the brain can cause neuronal damage, which can be partially reversed by relieving the stress via tumour removal or by administering lithium.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Solid stress in brain tumours.

References

  1. Bilston, L. E., Liu, Z. & Phan-Thien, N. Biorheology 34, 377–385 (1997).

    Article  CAS  Google Scholar 

  2. Ruoslahti, E. Glycobiology 6, 489–492 (1996).

    Article  CAS  Google Scholar 

  3. Seano, G. et al. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-018-0334-7 (2019).

  4. Broders-Bondon, F., Ho-Bouldoires, T. H. N., Fernandez-Sanchez, M. E. & Farge, E. J. Cell Biol. 217, 1571–1587 (2018).

    Article  CAS  Google Scholar 

  5. Nia, H. T. et al. Nat. Protoc. 13, 1091–1105 (2018).

    Article  CAS  Google Scholar 

  6. Pepin, K. M. & McGee, K. P. Top. Magn. Reson. Imaging 27, 353–362 (2018).

    Article  Google Scholar 

  7. Basan, M., Risler, T., Joanny, J. F., Sastre-Garau, X. & Prost, J. HFSP J. 3, 265–272 (2009).

    Article  Google Scholar 

  8. Pogoda, K. et al. New J. Phys. 16, 075002 (2014).

    Article  Google Scholar 

  9. Streitberger, K. J. et al. PLoS ONE 9, e110588 (2014).

    Article  Google Scholar 

  10. Arani, A. et al. Magn. Reson. Med. 79, 1043–1051 (2017).

    Article  Google Scholar 

  11. Ulrich, T. A., de Juan Pardo, E. M. & Kumar, S. Cancer Res. 69, 4167–4174 (2009).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, PA, USA

    Paul A. Janmey & Katarzyna Pogoda

  2. Departments of Physiology and Physics & Astronomy, University of Pennsylvania, Philadelphia, PA, USA

    Paul A. Janmey

  3. Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland

    Katarzyna Pogoda

Authors
  1. Paul A. Janmey
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Katarzyna Pogoda
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Paul A. Janmey.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Janmey, P.A., Pogoda, K. Compressive tumours cause neuronal damage. Nat Biomed Eng 3, 171–172 (2019). https://doi.org/10.1038/s41551-019-0370-y

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41551-019-0370-y

Search

Advanced search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer