Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Optical imaging: Resolutely deep and fast

Functionalized quantum dots emitting short-wavelength infrared light enable small-animal imaging with deep penetration, high spatial resolution and fast acquisition speeds.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Figure 1: Functionalized core–shell QDs for SWIR imaging.
Figure 2


  1. 1

    Rosenthal, E. L. et al. Clin. Cancer Res. 21, 3658–3666 (2015).

    CAS  Article  Google Scholar 

  2. 2

    Alander, J. T. et al. Int. J. Biomed. Imaging 2012, 940585 (2012).

    Article  Google Scholar 

  3. 3

    Sevick-Muraca, E. M. Annu. Rev. Med. 63, 217–231 (2012).

    CAS  Article  Google Scholar 

  4. 4

    Sevick-Muraca, E. M., Kwon, S. & Rasmussen, J. C. J. Clin. Invest. 124, 905–914 (2014).

    CAS  Article  Google Scholar 

  5. 5

    Zhu, B. & Sevick-Muraca, E. M. Br. J. Radiol. 88, 20140547 (2015).

    CAS  Article  Google Scholar 

  6. 6

    Antaris, A. L. et al. Nat. Mater. 15, 235–242 (2016).

    CAS  Article  Google Scholar 

  7. 7

    Jacques, S. L. Phys. Med. Biol. 58, R37–R61 (2013).

    Article  Google Scholar 

  8. 8

    Welsher, K. et al. Nat. Nanotech. 4, 773–780 (2009).

    CAS  Article  Google Scholar 

  9. 9

    Naczynski, D. J. et al. Nat. Commun. 4, 2199 (2013).

    CAS  Article  Google Scholar 

  10. 10

    Imamura, Y. et al. Molecules 21, 1080 (2016).

    Article  Google Scholar 

  11. 11

    Zhang, Y. et al. ACS Nano 6, 3695–3702 (2012).

    CAS  Article  Google Scholar 

  12. 12

    Allen, P. M. et al. J. Am. Chem. Soc. 132, 470–471 (2010).

    CAS  Article  Google Scholar 

  13. 13

    Bruns, O. T. et al. Nat. Biomed. Eng. 1, 0056 (2017).

    Article  Google Scholar 

  14. 14

    Zhu, B., Rasmussen, J. C., Litorja, M. & Sevick-Muraca, E. M. IEEE Trans. Med. Imaging 35, 802–811 (2016).

    Article  Google Scholar 

  15. 15

    Hong, G. et al. Nat. Med. 18, 1841–1846 (2012).

    CAS  Article  Google Scholar 

Download references

Author information



Corresponding author

Correspondence to Eva M. Sevick-Muraca.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Sevick-Muraca, E. Optical imaging: Resolutely deep and fast. Nat Biomed Eng 1, 0064 (2017).

Download citation


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing