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Microbispofurans A–C, plant growth-promoting furancarboxylic acids from plant root-derived Microbispora sp.

The Journal of Antibiotics volume 76, pages 392–396 (2023)Cite this article

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Abstract

Microbispofurans A–C (1–3), new alkyl/alkenyl furancarboxylic acids, were isolated from the culture extract of the plant root-derived Microbispora sp. RD004716. The planar structures of 1–3 were determined by extensive analysis of 1D and 2D NMR spectroscopic data. Although 1–3 showed no appreciable antimicrobial activity or cytotoxicity, strong plant growth-promotion activity of the germinated red leaf lettuce seeds was observed at 10 μM. Furancarboxylic acids and their methyl esters were found in actinomycetes and fungi; however, the isolation of furandicarboxylic acid was unprecedented.

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Acknowledgements

P388 cells were obtained from JCRB Cell Bank under accession code JCRB0017 (Lot. 06252002).

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  1. Biotechnology Research Center and Department of Biotechnology, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama, 939-0398, Japan

    Enjuro Harunari, Shunsuke Mae & Yasuhiro Igarashi

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Correspondence to Yasuhiro Igarashi.

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Harunari, E., Mae, S. & Igarashi, Y. Microbispofurans A–C, plant growth-promoting furancarboxylic acids from plant root-derived Microbispora sp.. J Antibiot 76, 392–396 (2023). https://doi.org/10.1038/s41429-023-00614-1

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