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Cotranscriptional splicing regulation: it's not just about speed

Nature Structural & Molecular Biology volume 13, pages 952–953 (2006)Cite this article

Recent data suggest that the C-terminal domain of RNA polymerase II can repress exon inclusion via a mechanism not explained by the prevailing models for cotranscriptional splicing regulation.

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Figure 1: Kinetic model for transcription-dependent alternative splicing.
Figure 2: Alternative models for transcription-dependent alternative splicing (diagrammed as in Fig. 1.

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  1. the Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, 75390-9038, Texas, USA

    Kristen W Lynch

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  1. Kristen W Lynch
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Lynch, K. Cotranscriptional splicing regulation: it's not just about speed. Nat Struct Mol Biol 13, 952–953 (2006). https://doi.org/10.1038/nsmb1106-952

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