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Inflammation and fibrosis in adipose tissue of osteoarthritic joints

Nature Reviews Rheumatology volume 13, pages 325326 (2017) | Download Citation

The infrapatellar fat pad and other adipose tissues in close proximity to the joint have been linked with osteoarthritis (OA), but the nature of this relationship is unclear. Two new studies elucidate the features of intra-articular adipose tissues in OA and raise important questions for future investigations.

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The authors' work is supported by the Dutch Arthritis Foundation (LLP24; A.I.-F., M.K.) and the Innovative Medicine Initiative Joint Undertaking funded project Be The Cure (115142–2; A.I.-F.).

Author information


  1. Department of Rheumatology, Leiden University Medical Center, P. O. Box 9600, 2300 RC Leiden, Netherlands.

    • Andreea Ioan-Facsinay
    •  & Margreet Kloppenburg


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Competing interests

The authors declare no competing financial interests.

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Correspondence to Margreet Kloppenburg.

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