In a longitudinal study of 54,763 women followed up over 24 years, investigators found that the incidence of systemic lupus erythematosus (SLE) was higher in women with probable post-traumatic stress disorder (PTSD) (that is, reporting four to seven symptoms of PTSD) than in women not exposed to trauma (HR 2.87, 95% CI 1.31–6.28). They also found a strong association between trauma exposure, regardless of PTSD symptoms, and incident SLE (HR 2.87, 95% CI 1.31–6.28).
References
Roberts, A. L. et al. Association of trauma and posttraumatic stress disorder with incident systemic lupus erythematosus (SLE) in a longitudinal cohort of women. Arthritis Rheumatol. http://dx.doi.org/10.1002/art.40222 (2017)
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Onuora, S. Trauma and PTSD linked with SLE risk. Nat Rev Rheumatol 13, 632 (2017). https://doi.org/10.1038/nrrheum.2017.167
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DOI: https://doi.org/10.1038/nrrheum.2017.167
