Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Epidemiology

The effects of AIDS on the prevalence of rheumatic diseases

The transition of HIV and AIDS from a death sentence to a chronic disease has not come without problems. Rheumatologists need to be aware of the full spectrum of rheumatic diseases seen in patients with HIV and AIDS, and know the best strategies for disease management.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. UNAIDS Global Statistics Fact Sheet. UNAIDS [online] (2016).

  2. Yen, Y. F. et al. Incidence of autoimmune diseases in a nationwide HIV/AIDS patient cohort in Taiwan, 2000–2012. Ann. Rheum. Dis.http://dx.doi.org/10.1136/annrheumdis-2016-209815 (2016).

  3. Winchester, R., Bernstein, D. H., Fischer, H. D., Enlow, R. & Solomon, G. The co-occurrence of Reiter's syndrome and acquired immunodeficiency. Ann. Intern. Med. 106, 19–26 (1987).

    Article  CAS  Google Scholar 

  4. Huang, Y. M. et al. Autoimmunity and dysmetabolism of human acquired immunodeficiency syndrome. Immunol. Res. 64, 641–652 (2016).

    Article  CAS  Google Scholar 

  5. Fox, C. & Walker-Bone, K. Evolving spectrum of HIV-associated rheumatic syndromes. Best Pract. Res. Clin. Rheumatol. 29, 244–258 (2015).

    Article  Google Scholar 

  6. Walker, N. F., Scriven, J., Meintjes, G. & Wilkinson, R. J. Immune reconstitution inflammatory syndrome in HIV-infected patients. HIV AIDS (Auckl.) 7, 49–64 (2015).

    Google Scholar 

  7. Lau, C. S. et al. Features of spondyloarthritis around the world. Rheum. Dis. Clin. North. Am. 24, 753–770 (1998).

    Article  CAS  Google Scholar 

  8. Yannam, G. R., Gutti, T. & Poluektova, L. Y. IL-23 infections, inflammation, autoimmunity and cancer: possible role in HIV-1 and AIDS. J. Neuroimmune Pharmacol. 7, 95–112 (2012).

    Article  Google Scholar 

  9. Cepeda, E. J., Williams, F. M., Ishimori, M. L., Weisman, M. H. & Reveille, J. D. The use of anti-tumour necrosis factor therapy in HIV-positive individuals with rheumatic disease. Ann. Rheum. Dis. 67, 710–712 (2008).

    Article  CAS  Google Scholar 

  10. Saberi, P., Phengrasamy, T. & Nguyen, D. P. Inhaled corticosteroid use in HIV-positive individuals taking protease inhibitors: a review of pharmacokinetics, case reports and clinical management. HIV Med. 14, 519–529 (2013).

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The authors thank the Shun Tak District Min Yuen Tong of Hong Kong for its generous donations to support their work on spondyloarthritis and immunodeficiency syndromes.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Chak-Sing Lau.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lau, CS., Li, P. The effects of AIDS on the prevalence of rheumatic diseases. Nat Rev Rheumatol 13, 8–10 (2017). https://doi.org/10.1038/nrrheum.2016.196

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrrheum.2016.196

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing