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Connective tissue diseases

Promises and challenges of metabolomics in SLE

Despite a multitude of confounding variables, common themes are emerging in metabolomic studies of systemic lupus erythematosus (SLE). Newly revealed metabolites and pathways are likely to complement the biomarkers and insights into SLE pathogenesis that are emerging from genomic, transcriptomic and proteomic studies.

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Acknowledgements

The authors would like to acknowledge U. Akbar for technical assistance in preparing this manuscript.

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Correspondence to Chandra Mohan.

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Ding, H., Mohan, C. Promises and challenges of metabolomics in SLE. Nat Rev Rheumatol 12, 627–628 (2016). https://doi.org/10.1038/nrrheum.2016.163

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