The risk of having vitamin D deficiency is more than threefold higher in patients with cutaneous lupus erythematosus (CLE) than in healthy individuals (OR 3.47, 95% CI 1.79–6.69), according to a new study (n = 177). However, the same study also showed that treatment of vitamin D insufficiency with oral vitamin D3 therapy for 1 year was associated with improvements in disease severity in 60 patients with CLE, according to patient and physician assessments, compared with 25 untreated patients with CLE.
References
Cutillas-Marco, E. et al. Vitamin D and cutaneous lupus erythematosus: effect of vitamin D replacement on disease severity. Lupus 10.1177/0961203314522338
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Vitamin D replacement improves cutaneous lupus. Nat Rev Rheumatol 10, 196 (2014). https://doi.org/10.1038/nrrheum.2014.28
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DOI: https://doi.org/10.1038/nrrheum.2014.28