Year in Review | Published:

Paediatric rheumatology in 2014

Digging deeper for greater precision and more impact in JIA

Nature Reviews Rheumatology volume 11, pages 7072 (2015) | Download Citation

Optimizing the management of childhood arthritis requires detailed knowledge of the disease in an individual patient. Advances in 2014 show how in-depth genetic studies and insights into immunopathogenesis could translate into clinical biomarkers and, eventually, individualized therapy.

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B.P. is supported by EUTRAIN (the 7th Framework programme of the EU), Marie Curie, Network for Initial Training (ITN) grant agreement No 289903, and by the Dutch Arthritis Foundation and the Understanding Childhood Arthritis Network (UCAN-U).

Author information


  1. Department of Paediatric Immunology & Laboratory for Translational Immunology, University Medical Centre Utrecht, PO Box 85090, 3508 AB Utrecht, Netherlands.

    • Berent Prakken
  2. Department of Paediatrics, University of Genova, IRCCS G. Gaslini, Largo G. Gaslini 5, 16147 Genova, Italy.

    • Alberto Martini


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Competing interests

B.P. has received speaker fees and/or has served as independent advisor for Amgen, Danone Research and Novo Nordisk. A.M. has in the past 3 years received honoraria and speakers' bureau fees from AstraZeneca, BMS, Boehringer Ingelheim, GSK, MedImmune, Novartis, Novo Nordisk and Sanofi Aventis; the GASLINI Hospital, of which A.M. is a full-time employee, has received support for the research activities of PRINTO from Abbott, AstraZeneca, Bristol–Myers Squibb, Eli Lilly and Company, 'Francesco Angelini' Foundation, GSK, Italfarmaco, Janssen Biologics B.V., Novartis, Pfizer Inc., Roche, Sanofi Aventis, Schwarz Biosciences GmbH, Xoma and Wyeth Pharmaceuticals.

Corresponding author

Correspondence to Berent Prakken.

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