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Regenerative medicine

Cartilage transplants hold promise for challenging bone defects

Nature Reviews Rheumatology volume 10, pages 129–130 (2014)Cite this article

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Unmet needs in fracture healing have led investigators to question existing paradigms in the hopes of uncovering overlooked solutions. Such is the case in a recent study showing that introduction of a cartilage construct into a mouse tibial defect induces remarkable healing owing to the transformation of donor chondrocytes into new bone.

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Figure 1: Cartilage grafts for segmental defect healing.

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Acknowledgements

The authors are supported by NIH grants P30 AR061307; P50 AR054041; and R01 DE019902.

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  1. The Center for Musculoskeletal Research, University of Rochester, 601 Elmwood Avenue, Box 665, Rochester, 14642, NY, USA

    Kohei Nishitani & Edward M. Schwarz

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  1. Kohei Nishitani
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  2. Edward M. Schwarz
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Correspondence to Edward M. Schwarz.

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The authors declare no competing financial interests.

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Nishitani, K., Schwarz, E. Cartilage transplants hold promise for challenging bone defects. Nat Rev Rheumatol 10, 129–130 (2014). https://doi.org/10.1038/nrrheum.2013.216

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