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Imaging in rheumatology in 2013

From images to data to theory

2013 has witnessed the maturation of imaging science with rheumatology research, in part due to large, public databases. Using imaging in osteoarthritis (OA) as an example, breakthroughs include further elucidation of the relationship between obesity and OA, and identification of the importance of bone and meniscus shape in OA development.

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Figure 1: Factors potentially involved in obesity-induced ROA.

References

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Acknowledgements

We thank all involved with the Osteoarthritis Initiative (OAI) for the public imaging data. The OAI is a public–private partnership comprising five contracts (N01-AR-2-2258; N01-AR-2-2259; N01-AR-2-2260; N01-AR-2-2261; N01-AR-2-2262) funded by the NIH, and conducted by the OAI Study Investigators. Private funding partners of the OAI include Merck Research Laboratories, Novartis Pharmaceuticals Corporation, GlaxoSmithKline and Pfizer. Private funding for the OAI is managed by the Foundation for the NIH. This manuscript was prepared using images from an OAI dataset and does not necessarily reflect the views of the OAI investigators, NIH, or private funders.

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Correspondence to Felix Eckstein.

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Felix Eckstein is Chief Executive Officer and Chief Marketing Officer of Chondrometrics GmbH, a company providing MRI analysis services to academic researchers and to industry. He has provided consulting services to MerckSerono, Abbvie, Sanofi Aventis and Novartis, and has received speaker honouraria from Medtronic and Synthes. He has received research support from Pfizer, Eli Lilly, MerckSerono, GlaxoSmithKline, Janssen Pharmaceuticals, Wyeth, Novartis, Stryker, Synarc and Kolon. C. Kent Kwoh has provided consulting services to Novartis and Pfizer.

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Eckstein, F., Kwoh, C. From images to data to theory. Nat Rev Rheumatol 10, 69–70 (2014). https://doi.org/10.1038/nrrheum.2013.198

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