An incident fracture sustained during treatment for osteoporosis does not necessarily represent treatment failure, an outcome that was redefined in 2012. Predictors of the new definition have now been reported and include ≥2 falls within the past year. Preventing fractures in the most at-risk patients, however, requires improved management strategies.
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P. Vestergaard declares that he has received grant/research support from Amgen, Eli Lilly, Novartis and Servier, and speakers' honoraria from Sanofi-Aventis.
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Vestergaard, P. Incident fractures during treatment for osteoporosis. Nat Rev Rheumatol 9, 508–510 (2013). https://doi.org/10.1038/nrrheum.2013.122
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DOI: https://doi.org/10.1038/nrrheum.2013.122