A meta-analysis that included data from 24 observational studies (7 cohort studies, 5 cross-sectional studies and 12 case–control studies) and a total of 20,997 individuals has shown that the overall risk of knee OA is significantly increased in those with a history of knee injury (odds ratio 4.20, 95% CI 3.11–5.66). Study design and definition of knee injuries did not affect the significance of the association.
ORIGINAL RESEARCH PAPER
Muthuri, S. G. et al. History of knee injuries and knee osteoarthritis: a meta-analysis of observational studies. Osteoarthritis Cartilage doi:10.1016/j.joca.2011.07.015
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Meta-analysis shows that previous knee injury significantly increases the risk of OA development. Nat Rev Rheumatol 7, 621 (2011). https://doi.org/10.1038/nrrheum.2011.158
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DOI: https://doi.org/10.1038/nrrheum.2011.158
