The diverse clinical symptoms associated with systemic lupus erythematosus (SLE) probably reflect its complex genetic underpinnings. Evidence from a new study indicates that analysis of common risk alleles can predict susceptibility to several end-organ manifestations of SLE, which could influence patient screening and support personalized approaches to treatment.
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Wakeland, E. Correlating genotypes with disease phenotypes in SLE. Nat Rev Rheumatol 7, 623–624 (2011). https://doi.org/10.1038/nrrheum.2011.142
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DOI: https://doi.org/10.1038/nrrheum.2011.142
