As of May 1, 2009, PubMed listed approximately 30,000 citations on the topic of vitamin D in humans, highlighting the medical community's avid interest in this field. Two articles published in the Archives of Internal Medicine diverge with previous reports on the prevalence of hypovitaminosis D and the capability of vitamin D to reduce fractures.
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References
Ginde, A. A., Liu, M. C. & Camargo, C. A., Jr. Demographic differences and trends of vitamin D insufficiency in the US population, 1988–2004. Arch. Intern. Med. 169, 626–32 (2009).
Looker, A. C. et al. Serum 25-hydroxyvitamin D status of the US population: 1988–1994 compared with 2000–2004. Am. J. Clin. Nutr. 88, 1519–1527 (2008).
Cranney, A. et al. Effectiveness and safety of vitamin D in relation to bone health. Evidence Report/Technology Assessment No. 158 (Agency for Healthcare Research and Quality, Rockville, MD, 2007).
Boonen, S. et al. Need for additional calcium to reduce the risk of hip fracture with vitamin D supplementation: evidence from a comparative metaanalysis of randomized controlled trials. J. Clin. Endocrinol. Metab. 92, 1415–1423 (2007).
Tang, B. M., Eslick, G. D., Nowson, C., Smith, C. & Bensoussan, A. Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis. Lancet 370, 657–666 (2007).
Bischoff-Ferrari, H. A. et al. Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials. Arch. Intern. Med. 169, 551–561 (2009).
Jackson, R. D. et al. Calcium plus vitamin D supplementation and the risk of fractures. N. Engl. J. Med. 354, 669–683 (2006).
Harwood, R. H., Sahota, O., Gaynor, K., Masud, T. & Hosking, D. J. A randomised, controlled comparison of different calcium and vitamin D supplementation regimens in elderly women after hip fracture: the Nottingham Neck of Femur (NONOF) study. Age Ageing 33, 45–51 (2004).
Law, M., Withers, H., Morris, J. & Anderson, F. Vitamin D supplementation and the prevention of fractures and falls: results of a randomised trial in elderly people in residential accommodation. Age Ageing 35, 482–486 (2006).
Porthouse, J. et al. Randomised controlled trial of calcium and supplementation with cholecalciferol (vitamin D3) for prevention of fractures in primary care. BMJ 330, 1003 (2005).
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Hansen, K. Prevalence of hypovitaminosis D and relationship to fracture. Nat Rev Rheumatol 5, 417–418 (2009). https://doi.org/10.1038/nrrheum.2009.143
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DOI: https://doi.org/10.1038/nrrheum.2009.143
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Vitamin D deficiency in early implant failure: two case reports
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