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A seminal study identifying truncated CPSF6 as a dominant negative inhibitor of infection, leading both to the appreciation of the role of CPSF6 in HIV-1 infection and to the N74D mutant, which remains a critical tool in studies in this area.
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A paper detailing the first identification of the TRIM–Cyp restriction factor, which has become an important tool in the study of uncoating, given its ability to recognize CA and be inhibited by CsA.
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