High stromal cellularity in pancreatic cancer is an important factor for ineffective treatment and molecular studies. In 2017, major advancements were made in transcriptional characterization, treatment delivery and clinical regimes, raising hope for a breakthrough against this deadly disease.
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The authors are supported by DFG grant (German research Foundation) SE-2616/2-1 (Germany) to A.S. and U01DK108328, U01CA117969, U01CA196403, and P01CA117969 to A.M.
The authors declare no competing financial interests.
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Semaan, A., Maitra, A. Rebooting pancreatic cancer knowledge and treatment options. Nat Rev Gastroenterol Hepatol 15, 76–78 (2018). https://doi.org/10.1038/nrgastro.2017.182
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