Research has highlighted the importance of the stroma in pancreatic cancer, in particular the role of complex interactions between cancer and stromal cells. A new study describes a novel mechanism by which stromal pathways can be modulated to inhibit tumour growth. The findings support the concept that a multipronged therapeutic approach targeting pancreatic cancer cells and cancer stroma could improve clinical outcomes for this disease.
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The authors acknowledge the support of grant funding from the National Health and Medical Research Council of Australia and the New South Wales Cancer Council.
The authors declare no competing financial interests.
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Apte, M., Wilson, J. A multipronged approach to pancreatic cancer treatment. Nat Rev Gastroenterol Hepatol 13, 385–387 (2016). https://doi.org/10.1038/nrgastro.2016.75
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