Measurements of liver copper content are considered the gold standard for diagnosis of Wilson disease. New evidence shows that a reduction of the diagnostic threshold indicative for Wilson disease potentially improves diagnostic accuracy.
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Stremmel, W., Merle, U. A new copper cut-off value for diagnosis of Wilson disease?. Nat Rev Gastroenterol Hepatol 12, 493–494 (2015). https://doi.org/10.1038/nrgastro.2015.132
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DOI: https://doi.org/10.1038/nrgastro.2015.132
